Descargar nomacs10/25/2022 ![]() ![]() The results of the survey were discussed within the same gynecologists and a panel of experts during eight macro-regional meetings. Seventy-seven Italian gynecologists were involved and asked to answer a survey to investigate some aspects related to contraception. Despite the benefits of E2, its use is still not so common among combined oral contraceptives (COC). This combination presents an improved effect on hemostasis and metabolism compared to ethinyl-estradiol (EE)-based products and may be considered a good option to meet women's needs in a more physiological way. Micronized estradiol (E2)/nomegestrol acetate (NOMAC) 24+4 is the first monophasic combined oral contraceptive pill containing natural E2, the same steroid produced by the granulosa cells of women ovaries. To minimize the risk of thrombosis-related adverse events, different formulations and doses have been investigated. Hormonal pills are among the most widely contraceptive methods used by women, despite the possible onset of different adverse events. Most results were comparable across all participating countries. The frequency of switching from 91-day COCLNG to CHCs or other contraceptives was generally low (5%-12%), with the highest proportion being among patients of French gynecologists.Ĭonclusions: Findings indicate that 91-day COCLNG was prescribed for relatively short durations and predominantly as indicated for contraception. Use of COC during the six months prior to 91-day COCLNG initiation was 14% across GP databases, but was lower (8%) in the French gynecologist database. The most common indication was contraception (42%-81%), followed by menstrual migraines (2%-14%). Across databases, 46%-76% of women were prescribed a single 91-day COCLNG prescription and median treatment duration ranged from 3-6 months. ![]() Results: A total of 235, 220, 207 and 659 women using 91-day COCLNG were identified in French, Italian and Belgian GP and French gynecologist databases, respectively. Prescribing patterns of 91-day COCLNG were examined including: (1) treatment duration (2) indication (3) use of combined oral contraceptive (COC) before 91-day COCLNG initiation and (4) switch from and to combined hormonal contraceptives (CHC) or other contraceptives. The study population included women receiving ≥1 prescription of 91-day COCLNG during the study period. Methods: A retrospective observational study was conducted in France, Italy and Belgium using electronic medical record databases obtained from general practitioners (GPs) in all participating countries and gynecologists in France from 2015-2018. Objective: As part of the risk management plan in Europe, this study was conducted to characterize drug utilization patterns of Seasonique, a 91-day extended levonorgestrel-containing combined oral contraceptive (COCLNG). ![]()
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